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Call for Applications: Broad Pragmatic Studies Funding (US)

Researchers collaborating in a modern lab setting, working on comparative clinical effectiveness research to improve patient outcomes. The scene highlights teamwork, advanced technology, and dedication to addressing critical health issues.


The Patient Centered Outcomes Research Institute (PCORI) is inviting applications for high-quality comparative clinical effectiveness research projects.

Category

Grant

Topic & Themes

The BPS PFA welcomes all investigator-initiated research in patient-centered comparative clinical effectiveness. The following Topic Themes are encouraged but not limited to:

Populations:

  • Improving outcomes for people with intellectual and developmental disabilities (IDD)
  • Promoting health for older adults
  • Promoting healthy children and youth

Health Behaviors:

  • Addressing substance use
  • Addressing violence and trauma

Health Conditions:

  • Addressing COVID-19
  • Addressing rare diseases
  • Improving cardiovascular health
  • Improving mental and behavioral health
  • Managing pain
  • Preventing maternal morbidity and mortality (MMM)
  • Promoting sleep health

Special Areas of Emphasis

  • Social Isolation and Loneliness in Older Adults: Testing interventions to address social isolation and loneliness in older adults.
  • Health Communication Strategies for Uptake of COVID-19 Vaccine: Comparing health communication strategies to promote COVID-19 vaccine uptake among U.S. adults and children.
  • Promoting Sleep Health in Inpatient Settings: Addressing sleep disturbance in inpatient settings to improve health outcomes.

Funding Information

  • Category 1: Supports research projects with direct costs up to and including $5 million.
  • Category 2: Supports research projects with direct costs greater than $5 million and up to $12 million, requiring justification of the need for additional funds.
  • Category 3: Supports research projects with direct costs up to $12 million using PCORnet for observational studies and/or pragmatic trials on a national scale.

Eligibility Criteria

Applications may be submitted by academic research entities, private sector research organizations, federal government agencies, nonprofit and for-profit research organizations, and colleges and universities.

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